上海應(yīng)用技術(shù)大學(xué)化學(xué)與環(huán)境工程學(xué)院導(dǎo)師：殷燕 正文

[導(dǎo)師姓名]
殷燕

[所屬院校]
上海應(yīng)用技術(shù)大學(xué)

[基本信息]
導(dǎo)師姓名：殷燕
性別：女
人氣指數(shù)：7746
所屬院校：上海應(yīng)用技術(shù)大學(xué)
所屬院系：化學(xué)與環(huán)境工程學(xué)院
職稱：副教授
導(dǎo)師類型：
招生專業(yè)：制藥工程
研究領(lǐng)域：本實(shí)驗(yàn)室綜合運(yùn)用計(jì)算機(jī)輔助藥物設(shè)計(jì)、化學(xué)合成、活性測試、代謝研究等方法開發(fā)抗流感病毒、降血...

[通訊方式]
辦公電話：13482609592
電子郵件：yinyan@sit.edu.cn

[個(gè)人簡述]
女，副教授。主講的研究生課程有《現(xiàn)代制藥工程實(shí)驗(yàn)》。已在JMC、JOC、DyesandPigments、AcsMed.Chem.Lett.Synthesis、BMC、BMCL、Tetrehedron、JFC、Chin.J.Chem.、Heterocycles、synth.Commun.、J.Heterocycl.Chem.等國際著名期刊上發(fā)表SCI論文30多篇，申請專利20多項(xiàng)，授權(quán)4項(xiàng)。在美國化學(xué)會(huì)國際大會(huì)、國際氟化學(xué)大會(huì)等會(huì)議上發(fā)表論文10多篇。累計(jì)主持國家級(jí)、省部級(jí)和校級(jí)研究項(xiàng)目20余項(xiàng)。

[科研工作]
在研項(xiàng)目（2017年）（1）“高活性的、ROCK2/1亞型選擇性的ROCK2抑制劑的設(shè)計(jì)與合成研究”，2016年國家自然基金，負(fù)責(zé)人。(2)‘“可再生燃料電池用一體化雙功能催化劑的開發(fā)”，上海市科促會(huì)2016年聯(lián)盟計(jì)劃，負(fù)責(zé)人。(3)“3,3’-聯(lián)二噻吩衍生物的合成及其應(yīng)用研究”，2016年上海市分子催化和功能材料重點(diǎn)實(shí)驗(yàn)室研究基金，負(fù)責(zé)人。（4）“含氟Limk1抑制劑的設(shè)計(jì)、合成及應(yīng)用研究”，2017年中國科學(xué)院有機(jī)氟化學(xué)重點(diǎn)實(shí)驗(yàn)室開放基金,負(fù)責(zé)人。（5）“基于“應(yīng)用型”本科人才培養(yǎng)的《高分子材料基礎(chǔ)》課程教學(xué)改革的探索與實(shí)踐”，2015年上海應(yīng)用技術(shù)學(xué)院校級(jí)教改項(xiàng)目，負(fù)責(zé)人。(6)“關(guān)于提高學(xué)術(shù)學(xué)位研究生創(chuàng)新能力的探索與實(shí)踐”，2016年上海應(yīng)用技術(shù)學(xué)院研究生教改項(xiàng)目，負(fù)責(zé)人。(7)“阿司匹林的制備及其質(zhì)量控制”，2016年校企合作實(shí)驗(yàn)項(xiàng)目，負(fù)責(zé)人。(8)“大學(xué)生科創(chuàng)與制藥工程專業(yè)應(yīng)用型人才培養(yǎng)模式研究”，2016年上海應(yīng)用技術(shù)大學(xué)高教課題，負(fù)責(zé)人。代表性論文（1）FengkaiCheng,YanYin*,GuozhenZhang,*,YuanWang,WeiDeng,FanhongWu“Optoelectronicandthermalpropertiesofhighlyfluorescenceemissive2,2’-distyryl-[3,3']-bithiophenes“Dyesandpigments2017,140,222-228(SCI,IF=4.0).（2）RuihongTao,YanYin*,YongbinDuan,YuxingSun,YueSun,FengkaiCheng,JinpengPan,ChenLu,YuanWangTetrahedron2017，10.1016/j.tet.2017.02.030（SCI,IF=2.6）(3)ZhaoZhao,JiaxinCui,YanYin,*HengZhang,YechengLiu,RuiZeng,ChaoFang,ZhenpengKai,ZhonghuaWang,*FanhongWua*“Synthesisandbiologicalevaluationofgem-difluoromethylenatedstatinderivativesashighlypotentHMG-CoAreductaseinhibitorsChin.J.Chem.2016,34,801-808(SCI,IF=1.9).(4)GuofengSun,FengkaiCheng,RuihengTao,YuxingSun,JinpengPang,Zhonghua,YaohuaZhu,ZhonghuaWang,FanhongWu,YanYin*“Superacid-catalyzedTandemMeyer-SchusterRearrangement/IntramolecularHydroaminationofo-AniliopropargyAlcoholstoSynthesize2,3-Dihydro-4(1H)-quinolones”Synth.Commun.2016,46,1249-1256(SCI,IF=1.0).(5)YanYin,KeZheng,NibalEid,ShannonHoward,Ji-HakJeong,FeiYi,JiaGuo,ChuiMinPark,MathieuBibian,WeilinWu,PamelaHernandez,HaJeungPark,YuntaoWu,Jun-LiLuo,PhilipV.Lograsso,YangboFeng“Bis-arylderivativesaspotentandselectiveLimkinaseinhinitors”J.Med.Chem.2015,58,1846-1861.(SCI,IF=5.6)(6)MeiDing,YanYin*,FanhongWu,JiaxingCui,HongZhou,GuofengSun,YuJiang,YangboFeng*“Discoveryofpotentandselectiveurea-basedROCKinhibitors:Exploringtheinhibitor’spotencyandROCK2/PKAselectivityby3D-QSAR,moleculardockingandmoleculardynamicssimulations”Bioorg.Med.Chem.2015,23,2505-2517(SCI,IF=2.9).(7)JiaxinCui,MeiDing,YanYin*,WeiDeng,ZhonghuaWang,YuJiang,HongZhou,GuofengSun,YangboFeng“Discoveryofbis-aryureaderivativesaspotentandselectiveLimkinhibitors:ExploringLimk1activityandLimk1/ROCK2selectivitythroughcomputationalstudies”Bioorg.Med.Chem.2015,23,7464-7477(SCI,IF=2.9)(8)YanYin*,HongZhou,XichenLiu,HaiyingChen,FanhongWu,HengZhang,RuihengTao,FengkaiCheng,YangboFeng“AMetal-FreeandRecyclableSynthesisofBenzothiazolesusingThioureaasaSulfurSurrogate”TetrahedronLett,2015,56,1709-1712.(SCI,IF=2.4)(9)YanYin*,HongZhou,GuofengSun,XichenLiu“m-CPBAMediatedIntramolecularAminohydroxylationofN-SulfonylAminoalkenestoSynthesizeβ-hydroxylCyclicAmines”JournalofHeterocyclicChemistry2015,1337-1345(SCI,IF=0.8)(10)YanYin*,Guo-FengSun,HengZhang,HongZhou,Fan-Hong,Wu“EnatioselectiveChalcogeno-Baylis-HillmanReactionofBenzaldehydeswithMVKandAcrylatesCatalyzedbyChiralThiepin-TiCl4Complex”Chin.J.Chem.2014,32,365-369.(SCI,IF=1.9)(11)YanYinLiLinClaudiaRuizSusanKhanMichaelDCameronWayneGrantJenniferPocasNibalEidHajeungParkThomasSchroeterPhilipV.LoGrassoYangboFeng“SynthesisandBiologicalEvaluationofUreaDerivativesasHighlyPotentandSelectiveRhoKinaseInhibitors”J.Med.Chem.2013,56,3568-3581。（SCI,IF=5.6）(12)YanYin,MichaelD.Cameron,LiLin,SusanKhan,ThomasSchrter,WayneGrant,JenniferPocas,YenTingChen,StephanSchrer,AlokPachori,PhilipLoGrasso*,YangboFeng*“DiscoveryofHighlyPotentandSelectiveUrea-basedROCKinhibitorsandtheireffectsontheintraocularpressureinrats”ACSMed.Chem.Lett.2010,1,175-179.(SCI,IF=3.2)(13)YanYin,LiLin,ClaudiaRuiz,MichaelD.Cameron,JenniferPocas,WayneGrant,ThomasSchrter,WeiminChen,DerekDuckett,StephanSchrer,PhilipLoGrasso,YangboFeng*“BenzothiazolesasRho-associatedkinase(ROCK-II)inhibitors”Bioorg.Med.Chem.Lett.2009,19,6686-6690.(SCI,IF=2.4)(14)YanYin,ZhuoChai,Wen-YingMa,GangZhao*“Synthesisofindolesviadiethylzinc-mediatedintramolecularhydroaminationreactionofalkynylsulfonamides”Synthesis2008,24,4036-4040.(15)YanYin,WenyingMa,ZhuoChai,GangZhao*“Et2Zn-CatalyzedIntramolecularHydroaminationofAminoalkynesandTandemCyclization/NucleophilicAdditionthroughtheIndoleZincSaltIntermediate”J.Org.Chem.2007,72,5731-5736.(16)YanYin,GangZhao*“HeptadecafluorooctanesulfonicAcid(C8F17SO3H)CatalyzedIntramolecularHydroaminationofOlefinicSulfonamidesinFluorousBiphaseSystem(FBS)”J.FluorineChem.2007,128,40-45.(17)YanYin,GangZhao*’”PerfluoroussuperacidC8F17SO3H-catalyzedintramolecularhydroaminationreactionofN-protected2-alkynylanilines:anovelsyntheticmethodforindoles”ChimicaOggi-ChemistryToday2007,25,42-45.(18)YanYin,GangZhao*“SynthesisofIndolinesandQuinolineviaCyclizationofN-Arylsulfonyl-2-allylanilinesCatalyzedbyBrnstedAcid”Heterocycles2006,68,23-31.

[教育背景]
1998年本科畢業(yè)于四川大學(xué)化學(xué)系，2007年到美國的Emory大學(xué)進(jìn)行博士后研究。 以上老師的信息來源于學(xué)校網(wǎng)站，如有更新或錯(cuò)誤，請聯(lián)系我們進(jìn)行更新或刪除，聯(lián)系方式

上海應(yīng)用技術(shù)大學(xué)

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