姓名：徐志卿性別：男職稱：教授招生院所：基礎(chǔ)醫(yī)學(xué)院招生類型：科學(xué)學(xué)位(博)科學(xué)學(xué)位(碩)招生專業(yè)：神經(jīng)生物學(xué)(博)神經(jīng)生物學(xué)(碩)研究方向名稱：神經(jīng)遞質(zhì)受體和重大腦病電子信箱：zhiqingx@ccmu.edu.cn

社會(huì)任職

1.中國(guó)神經(jīng)科學(xué)學(xué)會(huì)理事

2.中國(guó)生理學(xué)會(huì)學(xué)術(shù)委員會(huì)、轉(zhuǎn)化神經(jīng)科學(xué)專業(yè)委員會(huì)和外事工作委員會(huì)委員

3.北京神經(jīng)科學(xué)學(xué)會(huì)常務(wù)理事

4.北京海外高層次人才協(xié)會(huì)理事

個(gè)人簡(jiǎn)歷

1.199112-199709:瑞典卡羅琳斯卡醫(yī)學(xué)院神經(jīng)科學(xué)系博士生,博士學(xué)位

2.199709-199909:瑞典卡羅琳斯卡醫(yī)學(xué)院神經(jīng)科學(xué)系博士后

3.199909-200109:瑞典卡羅琳斯卡醫(yī)學(xué)院醫(yī)學(xué)生化和生物物理系博士后

4.200109-200707:瑞典卡羅琳斯卡醫(yī)學(xué)院神經(jīng)科學(xué)系Forskare(研究員)

5.200110-:中國(guó)科學(xué)院神經(jīng)科學(xué)研究所客座研究員

6.200112-:華中科技大學(xué)兼職教授

7.200702-:首都醫(yī)科大學(xué)神經(jīng)生物學(xué)系特聘教授

重要學(xué)術(shù)論文

1.WangYJ,LiH,YangYT,TieCL,LiF,XuZ-QD*（徐志卿）,WangCY..AssociationofGalaninandMajorDepressiveDisorderintheChineseHanPopulation.Plosone.2013,8(2):e57042.SCI

2.FuW,LeMaîtreE,FabreV,BernardJF,XuZ-QD*（徐志卿）,HökfeltT..Chemicalneuroanatomyofthedorsalraphenucleusandadjacentstructuresofthemousebrain.JCompNeurol.2010,518(17):3464-2494.SCI

3.XiaS，DunX-P，HuP-S,KjaerS,ZhengK,QianY,SolénC,XuT,FredholmB,HokfeltT,andXuZ-QD(徐志卿）*.PostendocytotictrafficofthegalaninR1receptor:alysosomalsignalmotifonthecytoplasmicterminus..ProcNatlAcadSciUSA.2008,105:5609-13.SCI

4.HuangHP,WangSR,YaoW,ZhangC,ZhouY,ChenXW,ZhangB,XiongW,WangLY,ZhengLH,LandryM,HokfeltT,XuZ-QD(徐志卿）,ZhouZ.Longlatencyofevokedquantaltransmitterreleasefromsomataoflocuscoeruleusneuronsinratpontineslices.ProcNatlAcadSciUSA.2007,104:1401-1406.SCI

5.LundstromL,SollenbergU,BrewerA,KouyaPF,ZhengK,XuXJ,ShengX,RobinsonJK,Wiesenfeld-HallinZ,XuZ-QD(徐志卿）,HokfeltT,BartfaiT,LangelU.Agalaninreceptorsubtype1specificagonist..Internationaljournalofpeptideresearchandtherapeutics.2005,11:17-27.SCI

6.SwansonCJ,BlackburnTP,ZhangX,ZhengK,XuZ-QD(徐志卿）,HokfeltT,WolinskyTD,KonkelMJ,ChenH,ZhongH,WalkerMM,DurkinM,ArtymyshynRP,SmithKE,JonesKJ,CraigDA,GeraldCP,BrancheckTA.FromTheCover:Anxiolytic-andantidepressant-likeprofilesofthegalanin-3receptor(Gal3)antagonistsSNAP37889andSNAP398299..ProcNatlAcadSciUSA.2005,102:17489-17494.SCI

7.XiaS,KjaerS,ZhengK,HuPS,XuT,HokfeltT,XuZ-QD(徐志卿）*.Constitutiveandligand-inducedinternalizationofEGFP-taggedgalaninR2andRlreceptorsinPC12cells..Neuropeptides.2005,39:173-178.SCI

8.ZhengK,KuteevaE,XiaS,BartfaiT,HokfeltT,XuZ-QD(徐志卿）*.Age-relatedimpairmentsofsynapticplasticityinthelateralperforantpathinputtothedentategyrusofgalaninoverexpressingmice..Neuropeptides.2005,39:259-267.SCI

9.XiaS,KjaerS,KangZ,HuP-S,BaiL,JiaJ,RiglerR,PramanikA,XuT,HokfeltT,XuZ-QD(徐志卿）*.VisualizationofafunctionallyenhancedGFP-taggedgalaninR2receptorinPC12cells:Constitutiveandligand-inducedinternalization..ProcNatlAcadSciUSA.2004,101:15207-15212.SCI

10.XiaS,XuL,BaiL,XuZ-QD(徐志卿）,Xu,T.Labelinganddynamicimagingofsynapticvesicle-likemicrovesiclesinPC12cellsusingTIRFManalysis..BrainRes.2004,997:159-164.SCI

11.BaoL,JinS-X,ZhangC,WangL-H,XuZ-Z,ZhangF-X,WangL-C,NingF-S,CaiH-J,GuanJ-S,XiaoH-S,XuZ-QD,HeC,HokfeltT,ZhouZandZhangX.Activationofdelta-opioidreceptorsinducesreceptorinsertionandneuropeptidesecretion..Neuron.2003,37:121-133.SCI

12.FetissovS.O.,XuZ-QD(徐志卿）,ByrneL.C.,HassaniH.,ErnforsP.andHokfeltT.NPYtargetsinthehypothalamus.NitricoxidesynthesizingneuronsexpressY1receptor..JNeuroendocrinology.2003,15:754-760.SCI

13.KoppJ,XuZ-QD(徐志卿）,ZhangX,PedrazziniT,HerzogH,KresseA,WangH,WalshJ,HokfeltT.ExpressionofneuropeptideY1receptorintheCNSofrat,wildtypeandY1receptorknock-outmouse.Focusonimmunohistochemicallocalization..Neuroscience.2002,111:443-532.SCI

14.MaX,TongY-G,SchmidtR,BrownW,PayzaK,HodzicL,PouC,GodboutC,HokfeltT,XuZ-QD(徐志卿）*.Effectsofgalaninreceptoragonistsonlocuscoeruleusneurons..BrainRes.2001,919:169-174.SCI

15.KokaiaM,HolmbergK,NanobashviliA,XuZ-QD(徐志卿）,KokaiaZ,LendahlU,HilkeS,TheodorssonE,KahlU,BartfaiT,LindvallO,HokfeltT.Suppressedkindlingepileptogenesisinmicewithectopicoverexpressionofgalanin..ProcNatlAcadSciUSA.2001,98:14006-14011.SCI

16.LindgrenN,XuZ-QD(徐志卿）,Herrere-MarschitzM,HaycockJ,GoldsteinM,HokfeltT,FisoneG.DopamineD2receptorsregulatetyrosinehydroxylaseactivityandphosphorylationatSer40inratstriatum.EurJNeurosci.2001,13:773-780.SCI

17.ShiT-JS,TandrupT,BergmanE,XuZ-QD(徐志卿）,UlfhakeB,HokfeltT.Effectofperipheralnerveinjuryonneuronalcellnumbersandneuropeptideexpressioninmousedorsalrootganglia..Neuroscience.2001,105:249-263.SCI

18.XuZ-QD(徐志卿）*,TongY-G,HokfeltT.Galaninenhancesnoradrenaline-inducedoutwardcurrentonlocuscoeruleusnoradrenergicneurons.Neuroreport.2001,12:1779-1782.SCI

19.LindgrenN,XuZ-QD(徐志卿）,LindskogM,Herrere-MarschitzM,GoinyM,HaycockJ,GoldsteinM,HokfeltT,FisoneG.RegulationoftyrosinehydroxylaseactivityandphosphorylationatSer19andSer40viaactivationofglutamateNMDAreceptorsinratstriatum..JNeurochem.2000,74:2470-2477.SCI

20.XuZ-QD(徐志卿)*,MaX,SoometsU,LangelU,HokfeltT.Electrophysiologicalevidenceforahyperpolarizing,galanin(1-15)-selectivereceptoronhippocampalCA3pyramidalneurons..ProcNatlAcadSciUSA.1999,96:14583-14587.SCI

21.XuZ-QD(徐志卿）,ShiTJ,HokfeltT.Galanin/GMAP-andNPY-likeimmunoreactivitiesinlocuscoeruleusandnoradrenergicnerveterminalsinthehippocampalformationandcortexwithnotesonthegalanin-R1and-R2receptors..JCompNeurol.1998,392:227-251.SCI

22.ShiTJ,HolmbergK,XuZ-QD(徐志卿）,SteinbuschH,deVenteJ,HokfeltT.EffectofperipheralnerveinjuryoncGMPandnitricoxidesynthaselevelsinratdorsalrootganglia:timecourseandcoexistence..Pain.1998,78:171-180.SCI

23.XuZ-QD(徐志卿）,ZhangX,PieriboneVA,GrillnerS,HokfeltT.Galanin-5-hydroxytryptamineinteractions:electrophysiological,immunohistochemicalandinsituhybridizationstudiesonratdorsalrapheneuronswithanoteongalaninR1andR2receptors..Neuroscience.1998,87:79-94.SCI

24.XuZ-QD(徐志卿）,LewJY,HaradaK,AmanK,GoldsteinM,DeutchA,HaycockJW,HokfeltT.Immunohistochemicalstudiesonphosphorylationoftyrosinehydroxylaseincentralcatecholamineneuronsusingsite-andphosphorylationstate-specificantibodies..Neuroscience.1998,82:727-738.SCI

25.XuZ-QD(徐志卿）*,BartfaiT,LangelU,HokfeltT.Effectsofthreegalaninanalogsontheoutwardcurrentevokedbygalanininlocuscoeruleus..AnnNYAcadSci.1998,863:459-465.SCI

26.XuZ-QD(徐志卿）*,deVenteJ,SteinbuschH,GrillnerS,HokfeltT.TheNO-cGMPpathwayintheratlocuscoeruleus:electrophysiological,immunohistochemicalandinsituhybridizationstudies..EurJNeurosci.1998,10:3508-3516.SCI

27.XuZ-QD(徐志卿）*andHokfeltT.Expressionofgalaninandnitricoxidesynthaseinsubpopulationsofserotoninneuronsoftheratdorsalraphenucleus..JChemNeuroanat.1997,13:169-187.SCI

28.YamadaK,XuZ-Q(徐志卿）,ZhangX,GustafssonL,HultingAL,deVenteJ,SteinbuschHW,HokfeltT.NitricoxidesynthaseandcGMPintheanteriorpituitarygland:effectofaGnRHantagonistandnitricoxidedonors..Neuroendocrinology.1997,65:147-156.SCI

29.ShiTJ,ZhangX,HolmbergK,XuZ-QD(徐志卿）,HokfeltT.Expressionandregulationofgalanin-R2receptorsinratprimarysensoryneurons:effectofaxotomyandinflammation..NeurosciLett.1997,237:57-60.SCI

30.XuZ-QD(徐志卿）,ZhangX,GrillnerS,HokfeltT.Electrophysiologicalstudiesonratdorsalrootganglionneuronsafterperipheralaxotomy:changesinresponsestoneuropeptides..ProcNatlAcadSciUSA.1997,94:13262-13266.SCI

31.BaoL,KoppJ,ZhangX,XuZ-QD(徐志卿）,ZhangLF,WongH,WalshJ,HokfeltT.LocalizationofneuropeptideYY1receptorsincerebralbloodvessels.ProcNatlAcadSciUSA.1997,94:12661-12666.SCI

32.XuZ-Q(徐志卿）,ShiTJ,LandryM,HokfeltT.Evidenceforgalaninreceptorsinprimarysensoryneuronesandeffectofaxotomyandinflammation..Neuroreport.1996,8:237-242.SCI

33.XuZ-Q(徐志卿）,ShiTJ,HokfeltT.Expressionofgalaninandagalaninreceptorinseveralsensorysystemsandboneanlageofratembryos..ProcNatlAcadSciUSA.1996,93:14901-14905.SCI

34.PieriboneVA,XuZ-Q(徐志卿）,ZhangX,GrillnerS,BartfaiT,HokfeltT.Galanininducesahyperpolarizationofnorepinephrine-containinglocuscoeruleusneuronsinthebrainstemslice.Neuroscience.1995,64:861-874.

35.ZhangX,XuZ-Q(徐志卿）,BaoL,DagerlindA,HokfeltT.ComplementarydistributionofreceptorsforneurotensinandNPYinsmallneuronsinratlumbarDRGsandregulationofthereceptorsandpeptidesafterperipheralaxotomy.JNeurosci.1995,15:2733-2747.SCI

36.XuZ-Q(徐志卿）,PieriboneVA,ZhangX,GrillnerS,HokfeltT.Afunctionalrolefornitricoxideinlocuscoeruleus:immunohistochemicalandelectrophysiologicalstudies.ExpBrainRes.1994,98:75-83.

 

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